(S)-3-(Boc-Amino)Pyrrolidine, known by its CAS number 625471-18-3, plays a notable role as a protected amino compound in the pharmaceutical and specialty chemical sectors. The compound features a pyrrolidine ring with a (Boc) tert-butoxycarbonyl group, which stabilizes the amino moiety and permits selective reactions during drug synthesis. Industrial users regularly encounter this chemical listed under HS-Code 2933399990, a detail that streamlines international logistics and customs clearance. Laboratories frequently handle it as a white to off-white solid, where its solid state—flakes, powder, or crystalline form—offers flexible handling for both small-scale research and bulk manufacturing applications.
The molecular formula C9H18N2O2, combined with a typical molecular weight of 186.25 g/mol, anchors this compound's broad reactivity in peptide synthesis and asymmetric transformations. Chemically, it dissolves well in standard organic solvents, which makes solution preparation straightforward. Specific density sits around 1.1 g/cm³, supporting efficient mixing without the need for advanced machinery. More critically, synthesis routes outlined in literature benefit from this molecule’s stability offered by the Boc group—Boc, tert-butoxycarbonyl, offers temporary protection, simplifying deprotection steps downstream.
(S)-3-(Boc-Amino)Pyrrolidine sees heavy demand as a chiral intermediate. It features in API (active pharmaceutical ingredients) manufacturing, peptidomimetics, and fine chemical production. Synthetic chemists value it for its ability to introduce asymmetry into target molecules, key for bioactive compounds. GMP-certified manufacturers often market this compound as part of multi-step synthesis packages, targeting R&D labs and bulk pharmaceutical producers alike. Large buyers typically request TDS (Technical Data Sheets), SDS (Safety Data Sheets), and certifications like ISO, SGS, Halal, or Kosher as a sign of quality and regulatory compliance.
Major chemical factories in China handle a sizable portion of global exports for (S)-3-(Boc-Amino)Pyrrolidine. Extensive supply networks and advanced production lines allow Chinese suppliers to offer both competitive factory prices and high consistency in product quality. Market demand from Europe, the United States, India, and other pharmaceutical hubs connects with Chinese manufacturers seeking distribution agreements for bulk orders under CIF (Cost, Insurance, Freight) and FOB (Free on Board) terms. Inquiries for MOQs, distributor arrangements, OEM services, and even free samples often kick off partnerships and market expansion. Factories frequently maintain REACH registration and GMP-compliant status to keep up with rising buyer expectations for regulatory transparency and safety.
Hands-on experience handling raw chemicals underlines the significance of up-to-date MSDS documents. This compound poses moderate handling risks—common requirements include use of gloves, eye protection, and ventilated workspaces to manage inhalation, ingestion, and dermal exposure risks. Accurate labelling and regular training on chemical storage and spills stanch potential incidents. Most credible suppliers provide thorough SDS documentation, aligning with EU REACH, US OSHA, and GHS safety standards. Buyers regularly check certifications or third-party inspection results as part of the qualifying process, ensuring the batch in question matches purity claims and regulatory checklists.
Global pricing for (S)-3-(Boc-Amino)Pyrrolidine adapts to upstream feedstock prices, currency fluctuations, and policy changes impacting exports and tariffs. In my experience working with bulk chemical distributors, spot market prices and forward contracts vary, but Chinese supply routes hold down costs for most buyers seeking efficiency at scale. Supply chain disruptions—be it factory maintenance updates or new environmental standards—move quickly through industry news and affect lead times for buyers sourcing time-sensitive raw materials. Quality-focused buyers look for sample testing, small MOQs for research lots, and robust bulk quote options for scaling production. Wholesale rates reflect order size, destination, and certifications required for pharmaceutical, food, or industrial applications.
End-users often request detailed physical and chemical property sheets to confirm the suitability of (S)-3-(Boc-Amino)Pyrrolidine for new projects. Understanding material form—whether flakes, fine powder, or crystals—saves time selecting solubilization protocols or adapting to special process lines. Purity levels, water content, and documentation standards (COA, TDS, SDS, ISO, Halal, or Kosher) come up in procurement discussions. For those placing first-time orders with Chinese suppliers, a free sample or small sample purchase order secures verification of chemical quality before scaling up. Distributors and wholesalers usually offer prompt quotes upon receiving inquiry details, and some suppliers share reports, policy updates, and regulatory news for ongoing clients. Market demand remains healthy as downstream pharmaceutical and biochemical research grows worldwide, pressuring factories to maintain stable production rates year-round.
Navigating the global market for specialty chemicals such as (S)-3-(Boc-Amino)Pyrrolidine involves more than checking a price list. Establishing trusted supplier relationships, negotiating clear OEM or distributor contracts, and confirming certifications or GMP status avoid costly supply gaps. Partners delivering comprehensive support—from safe packaging to timely sample shipment—protect operations against sudden policy shifts or freight delays. Requests for SDS, TDS, and certification copies expedite audits and compliance checks, especially for regulated applications in Europe or North America. Personal experience shows that proactive suppliers who update clients with news of regulatory changes, process improvements, or market trends simplify the procurement cycle and improve long-term project planning.
