(S)-2-(4-Fluorophenyl) Pyrrolidine: Key Details for Buyers and Industry Insights

Understanding (S)-2-(4-Fluorophenyl) Pyrrolidine and Its Role as a Chemical Raw Material

(S)-2-(4-Fluorophenyl) Pyrrolidine, a compound featuring a fluorinated phenyl group attached to the pyrrolidine ring, attracts a lot of discussion in pharmaceutical research and specialty chemicals markets. The molecular formula C10H12FN places it within a class of intermediates known for supporting active pharmaceutical ingredient (API) synthesis. HS Code classification supports its movement through customs for global trade, with manufacturers in China consistently reporting its use as a fundamental building block. Molecular weight sits at 165.21 g/mol, supporting chemical reactions where specific density (typically around 1.13 g/cm³ in solid powder form) matters for scaling and process design. Suppliers produce it as flakes, solid powder, or rarely as pearls, each maintaining high purity as outlined in typical specification sheets and confirmed by ISO and SGS certifications. Getting the right structure in each batch can make the difference in research success, and repeat batches from GMP-certified manufacturers help guarantee this consistency.

Supplier-Manufacturer Dynamics: Pricing, Certification, and Factory Aspects

The bulk of (S)-2-(4-Fluorophenyl) Pyrrolidine on the market draws from GMP-compliant factories across Asia, especially China, where robust supply chains and lower factory prices trim costs for distributors and end users. Factory quotes usually list prices CIF or FOB, depending on pickup locations, and policy on negotiating MOQ (minimum order quantity) often becomes a crucial discussion point. Distributors tend to highlight ISO, REACH, and TDS documentation upfront for quality assurance, and halal/kosher status provides added value for certain regulated applications. MSDS (material safety data sheets) and SDS certificates play an important role too; downstream clients often demand a sample with complete documentation to assess safety profiles and hazardous properties before a wholesale or bulk purchase commitment. I’ve learned that working directly with a reliable manufacturer in China typically brings quick turnarounds on both samples and formal quotes.

Market Demand, Application, and Certification Considerations

Demand for (S)-2-(4-Fluorophenyl) Pyrrolidine remains steady in pharmaceutical raw material sectors. Its unique structure, with the fluorophenyl group boosting metabolic stability and selectivity, supports its use in drug discovery for both laboratory scale and commercial production. Bulk CIF prices have generally stayed competitive thanks to wide-scale factory output, flexibility on MOQ, and ongoing improvements in supply policies. In recent years, I’ve noticed Chinese suppliers put extra focus on GMP and OEM offers, aiming to support clients needing REACH and SGS-certified batches that fit international purchasing requirements. Halal and kosher certification has become essential for markets in Southeast Asia and the Middle East, driving up the need for distribution networks that offer certified, documented product lines. Market reports suggest that lab-scale users and corporate distributors desire not only the raw product but also detailed TDS and MSDS documents, so buyers must insist on a full paper trail.

Challenges in Handling, Hazardous Properties, and Storage Protocols

Working with (S)-2-(4-Fluorophenyl) Pyrrolidine means understanding both the chemical’s beneficial properties and its potential risks. Hazard classifications typically cite mild irritation to respiratory or dermal systems in raw form, with MSDS highlighting safe handling protocols, including PPE and proper ventilation. Material is usually packed in well-sealed drums, often solid powder or flakes, reducing the risk of exposure. From my own experience managing shipments from Asian suppliers, correct labeling and documentation are non-negotiable; I’ve seen customs reject whole consignments for missing or incomplete SDS paperwork. Chemical storage involves cool, dry, and stable conditions, away from incompatible substances, which helps preserve quality over months in transit or warehouse storage. Unlike many hazardous chemicals, properly packaged (S)-2-(4-Fluorophenyl) Pyrrolidine doesn’t usually pose major risks, though every buyer should request a TDS with specifics on appearance (powder, white to off-white), solubility profile, and storage best practices.

Purchasing, Sample Inquiry, and Supply Chain Transparency

Buyers entering the market for this compound often start with a sample or small MOQ to check quality and supplier responsiveness. Direct inquiry, rather than secondary market approaches, proves the most effective route for reliable supply. Good suppliers bring clear CIF or FOB price lists, flexibility on bulk order discounting, and updated market demand reports that track both pricing trends and overall availability. I have found emailing directly for sample quotes speeds up everything, as trusted factories reply with COA, MSDS, and batch data sheets almost immediately, including details for REACH, halal, kosher, and ISO/SGS compliance. As the China supply chain matures, more agents assist with OEM rebranding, free samples, and distributor partnership programs, so market entrants can move from inquiry to purchase to long-term supply without hurdles. Competition keeps sensitive materials like (S)-2-(4-Fluorophenyl) Pyrrolidine affordable, especially for users seeking GMP-documented, certified raw materials for regulated applications.

Concluding Observations on Quality Control, Certification, and Purchasing Best Practices

Reliable quality comes down to documentation, open communication with suppliers, and experience with international shipping of hazardous materials. Most manufacturers and suppliers worth their salt display ISO, SGS, and REACH status openly, accommodating requests for free samples and technical support. Supply chain transparency—regardless of whether the end use involves chemical synthesis, pharmaceutical R&D, or market resale—means every shipment should include COA, MSDS, and TDS documents, along with verifications of halal or kosher status where required. OEM and rebranding services help new distributors enter competitive spaces, expanding beyond just China market dynamics and enabling broader access. A solid relationship with a quality supplier, proven through consistent samples, clear quotes, and top-tier certification, proves more valuable than lowest headline price, especially when handling a compound as versatile—and as regulated—as (S)-2-(4-Fluorophenyl) Pyrrolidine.