(S)-2-(3-Iodophenyl)Pyrrolidine comes with the molecular formula C10H12IN and a structure characterized by a pyrrolidine backbone attached to a 3-iodophenyl group. As a solid raw material, this compound usually shows up in white or off-white flakes or powder, sometimes even crystalline flakes depending on purity. Specific density hovers around 1.7 g/cm³. Its melting point falls within standard lab handling ranges, which matters during recrystallization or quality testing. As someone who has spent hours in both research and production environments, holding a vial of this compound, MSDS (Material Safety Data Sheet) on hand, safety glasses up, I can vouch for the importance of the right handling protocol—iodinated aromatics never go unnoticed for their hazards and their regulatory red tape. The raw material sits neatly in a CAS listing, often traded under HS Code 29333999, tying it to broader import/export regimes worldwide.
Pricing discussions never stray far from China’s towering market share here. Suppliers running GMP-compliant plants push (S)-2-(3-Iodophenyl)Pyrrolidine out at factory FOB/CIF rates, depending on who’s at the other end. From my time negotiating with distributors, I noticed that MOQ (minimum order quantity) varies—some OEM and bulk buyers can negotiate flexible batches, but small-scale labs probably stick to kilogram or less lots. Global buyers always ask about ISO, SGS, Halal, or Kosher certifications, making a point about non-negotiables around quality and compliance. In practice, the most reputable Chinese manufacturers will readily share the REACH registration, SDS, TDS, and even batch-specific documents before you place that inquiry or sample order, showing transparency up front. The rapid response on quotes and sample shipment often leaves Western importers scrambling to keep up with the pace.
Every experienced chemist working in medicinal chemistry or custom synthesis recognizes this molecule as a core scaffold and critical building block for pharmaceutical intermediates. The 3-iodophenyl group makes it a versatile candidate for Suzuki couplings or further functionalization. Market demand tends to spike when research pivots toward next-generation CNS-active compounds. Formulations teams push for detailed material property specifications, especially when purity and chiral selectivity impact downstream yields in scale-up synthesis. End users in pharma or fine-chemical applications drill suppliers on stability, potential hazardous classification, and transport restrictions (especially given iodine’s notoriety). Market reports have shown growing sales volume year over year, fueled by ongoing R&D projects in North America, Europe, and Asia-Pacific, where China dominates both manufacturing volume and competitive pricing.
Not a week goes by in raw chemical procurement without someone asking for a comprehensive MSDS or SDS. (S)-2-(3-Iodophenyl)Pyrrolidine stakes its claim on both safe and hazardous lists, flagged for iodine’s potential reactivity and environmental impact. Proper ventilation, gloves, and goggles come as standard procedure in any legitimate operation. I recall reviewing TDS and MSDS documents on-site at a Suzhou supplier’s plant, watching as production runs triggered automatic batch sampling for ISO and GMP compliance checks. This level of documentation, from detailed hazard codes to handling recommendations, ends up shaping distribution policies. Compliance with REACH, SGS audited shipments, and transparent batch traceability top the requirements set by manufacturers supplying Europe or the United States. Halal and Kosher certifications surface in multinational OEM supply deals, especially for companies seeking market expansion into Middle East or Southeast Asia.
Entering this market means preparing to compare bulk pricing, shipping terms (CIF/FOB), and negotiating sample MOQs for validation. The quote cycle often runs from quick inquiry to dispatch within days if the supplier holds stock. Bulk buyers favor market-competitive rates from direct-from-factory sales, double-checking that batch certificates and ISO-compliant documentation come bundled. Distributors stake their margins on certificates (REACH, ISO, SGS, even OEM branding), which in turn opens doors to wider market segments looking for reliable, certified sources. Free samples and detailed TDS or COA (Certificate of Analysis) requests help establish trust early, and policy trends in major importing countries can shift purchasing patterns quickly. In my purchasing experience, observing demand for (S)-2-(3-Iodophenyl)Pyrrolidine surge alongside regulatory changes, research breakthroughs, or even policy tweaks around iodine precursors is not uncommon.
Sourcing any hazardous chemical from global suppliers always carries risk. Counterfeit certificates, inconsistent purity, and shipping delays can sink deals fast. Keeping ahead means sticking to suppliers with documented GMP, ISO, and verified SGS audit trails. Tools like real-time QA tracking, QR code batch verification, and in-house analytical testing help buyers filter genuine from suspect supplies. Aligning partners that provide upfront pricing transparency, responsive sample shipping, and robust market-demand data avoids costly missteps. Close cooperation with customs brokers and staying in sync with global raw material policy shifts can make the difference between smooth importation and regulatory headaches. Sharing insight with industry peers about price, specification shifts, and regional supply policies keeps everyone a step ahead in a sector where demand for (S)-2-(3-Iodophenyl)Pyrrolidine continues to accelerate.
