(S)-1-Cbz-Pyrrolidine-3-Carboxylic Acid, also known as (S)-1-benzylcarbonyloxypyrrolidine-3-carboxylic acid, offers a unique formula and molecular structure appreciated in pharmaceutical processes and advanced organic synthesis. Its chemical formula, C13H15NO4, supports a molecular weight of 249.26, distinguishing it from other intermediates in its class. The product appears as a white to off-white solid, sometimes found as flakes or powder, with a specific density typically around 1.3 g/cm³. Purity grades often reach above 98%. These physical characteristics matter to pharmaceutical producers and R&D experts who prioritize clear identity, traceable HS code references, and stable performance. For safe handling, consult its MSDS to check storage needs and hazard statements before every purchase, since this raw material can have harmful properties. Detailed REACH, ISO, and SGS certifications add transparency and build trust for buyers concerned about international safety and quality standards.
Talking to marketing leads at several major fine chemical manufacturers in China, there’s one thing that keeps cropping up: global buyers expect price stability, strict GMP processes, and a well-documented supply chain. Large chemical parks in Jiangsu and Zhejiang provinces house most of the leading (S)-1-Cbz-Pyrrolidine-3-Carboxylic Acid factories, and have become the go-to for both bulk and specialty orders. Factories with GMP certification and ISO documentation ship this intermediate across Europe and North America, often offering flexible options like CIF, FOB, and EXW terms, alongside small MOQ samples for early-stage R&D. Bulk supply from China can significantly lower acquisition costs. A reliable chemical buyer or distributor sees clear value sourcing directly from factories with factory pricing, OEM service, and third-party lab testing. Global chemical marketplace platforms often feature monthly market demand reports indicating that buyers from pharmaceutical and biotech markets are trending toward long-term supply agreements, thanks to consistently competitive prices and broad application use ranging from peptide manufacturing to custom synthesis.
Having worked with lab procurement for years, I put high value on robust SDS and TDS documentation, especially as many customers demand full traceability. Safety isn’t a checkbox; it’s right at the top of commercial conversations. Suppliers today highlight their ability to provide up-to-date MSDS documentation and batch-specific QC certificates. A good factory will also offer REACH, SGS, and sometimes halal or kosher certification for customers in Europe, Southeast Asia, or the Middle East. With quality certifications, you avoid regulatory headaches—especially when dealing with potential hazardous or harmful raw materials. Distribution partners with strong records for meeting ISO requirements consistently deliver compound solutions on time, and their attention to safe packaging and documentation often makes cross-border trade far less stressful.
Buyers entering this market look for three big things: up-to-date market news, transparent inquiry and sample procedures, and a clear quote on bulk purchases. I’ve watched many overseas procurement managers request free samples and small MOQ solutions to validate performance before scaling up. Most reputable Chinese distributors or manufacturers will respond quickly to online RFQs, providing full COA and TDS files with their offers. For new buyers, this reduces procurement anxiety. Transparent pricing, especially with bulk or wholesale quotes, keeps everyone honest and enables negotiation for long-term contracts. For larger projects, it’s easy to request a market demand report or sourcing policy update, making planning and investment much easier.
Most (S)-1-Cbz-Pyrrolidine-3-Carboxylic Acid purchases serve as high-grade intermediates for synthesizing APIs, peptides, and specialty fine chemicals. Over the past five years, an uptick in new-drug research, including custom peptide and beta-lactam projects, has boosted its demand, particularly as suppliers offer OEM and tailored raw material solutions. Labs focused on building new pharmaceuticals seek materials with reliable molecular property profiles so every batch supports their validation studies. Downstream users—from collegiate research labs up to multinationals—know a trustworthy supplier can offer more than just product: help with TDS, purity specs, or logistics smooths the research-to-pilot-scale ramp-up. That’s where end users save time, money, and avoid import risk. As use cases expand, demand from bulk buyers—distributors, contract manufacturers, and pharma API producers—remains strong. Specific requests arise for flakes, solid powder, or crystalline forms, since end-use applications range from solution preparation to solid-phase synthesis, and even niche liquidcrystal or pearls formats for innovative applications.
