(S)-1-Boc-2-Cyanopyrrolidine, best known for its role as a versatile chemical intermediate, has carved its niche in the pharmaceutical, chemical synthesis, and academic research industries. The structure reveals a Boc-protected pyrrolidine with a cyano group at the 2-position, translating into molecular formula C10H16N2O2 and a specific density that suits many synthesis processes. The material presents as a solid—sometimes found as white powder, flakes, or even crystalline pearls. Buyers checking its HS-Code for customs and compliance will often reference its solid form for logistics and storage safety.
Chinese manufacturers dominate the global supply of (S)-1-Boc-2-Cyanopyrrolidine. Visiting supplier listings from cities like Shanghai and Suzhou, it’s common to see monthly capacities scaling from laboratory grams up to tens of metric tons for pharmaceutical-grade supplies. GMP-certified factories, often with REACH, ISO, and SGS certifications, keep up with the quality assurance protocols global buyers require. Market demand reports show applications ranging from protected amino acid analogues to the production of inhibitors for enzyme-targeted drugs. Suppliers listing “factory price” usually carry batch-specific MSDS, with TDS and COA delivered upon inquiry. The supply chain specialists know CIF and FOB incoterms, bulk or liter solutions, and custom packaging to match export needs.
Chemists appreciate (S)-1-Boc-2-Cyanopyrrolidine as a key raw material in active pharmaceutical ingredient (API) synthesis. Its molecular property—specifically the tert-butoxycarbonyl (Boc) protection—lets the compound act as an efficient chiral building block, essential for asymmetric synthesis in pharmaceutical research. Synthetic schemes for antiretroviral drugs and enzyme inhibitors frequently specify this intermediate for its stability and selectivity. Knowing the MSDS remains crucial because the cyano group can show hazardous characteristics, requiring proper chemical handling and storage. A sample of the SDS outlines proper PPE use, incompatibility with strong acids or oxidizers, and instructions for spills or exposure incidents.
Product specification sheets detail appearance, assay percentage, melting point, specific density, and purity. Recent customer inquiries often prioritize specifications like minimum purity above 99%, verified by HPLC or NMR, before issuing a formal RFQ. Factories with OEM and custom synthesis capacity attract OEM orders by promising stable supply backed by continuous GMP certification and laboratory verification. Both halal and kosher certifications support global distribution to clients with specialized compliance needs. The market’s request for free samples, flexible MOQ (minimum order quantity), and direct purchase through distributors or wholesale channels reveals keen competition among suppliers. Distributors often keep a ready stock to serve urgent inquiries, responding with price quotes that reflect CIF or FOB ports in Asia, Europe, and North America.
A buyer, whether for R&D or commercial application, often starts with a sample request—suppliers from China have streamlined this process with online inquiry forms, sample pack delivery by express, and detailed documentation for safety and customs. Sales teams routinely explain the differences between pharmaceutical, industrial, and research grades, emphasizing batch traceability and regular ISO audits to reassure overseas customers. Many leading manufacturers include REACH pre-registration for the EU, SGS and TDS backing for international compliance, and send full documentation with every bulk order. Application notes show (S)-1-Boc-2-Cyanopyrrolidine’s flexibility in chemical synthesis for new drug molecules. This flexibility fuels demand, reflected in each new market report tracking year-over-year growth in pharmaceutical intermediates.
International buyers face issues such as hazardous goods transportation, local restrictions on cyanide-based reagents, and gaps in technical support. Many end-users move toward sourcing from GMP-validated factories where traceability reduces risks tied to product quality or regulatory challenge. Manufacturers respond with regular third-party quality audits, investing in training for logistics partners so that the chemical arrives with all safety data and labeling requirements followed. It is evident that ongoing supplier education about REACH, SDS, ISO, and halal/kosher criteria benefits customers who want minimal disruption and clear paths for regulatory import. This collective pursuit of transparent documentation, real-time tracking of shipments, and integrated safety management helps meet both immediate R&D deadlines and broader, long-term compliance needs.
