(S)-1-Boc-2-(Aminomethyl)Pyrrolidine: Chemical Supply, Application, and Market Considerations

Understanding (S)-1-Boc-2-(Aminomethyl)Pyrrolidine: Properties and Specifications

(S)-1-Boc-2-(Aminomethyl)Pyrrolidine, known by its CAS number 87120-72-7, draws attention from pharmaceutical developers and chemical synthesizers looking for enantiomerically pure building blocks. Its molecular formulaC10H20N2O2, density around 1.06g/cm³, and structure enable downstream applications in drug discovery and manufacturing. In my own years working with sourcing teams in pharma supply chains, this compound often stands out for its chiral purity—crucial for active pharmaceutical ingredient (API) synthesis. It appears as a crystalline solid, sometimes flakes or powder, and remains stable under regular conditions. Its HS Code 2933990099 marks it for customs and regulatory tracking, which matters during international shipment and compliance reporting.

Sourcing From China: Factory, Price, and Manufacturing Standards

Manufacturers and suppliers in China dominate global exports of (S)-1-Boc-2-(Aminomethyl)Pyrrolidine, thanks to robust factory capabilities and established GMP (Good Manufacturing Practice) systems. As a buyer or distributor, assessing supplier credentials—GMP compliance, ISO or SGS third-party certifications, and halal or kosher status—gives assurance that the material meets pharmaceutical supply chain standards. Prices often follow international raw material market conditions, but Chinese suppliers keep factory price competitive for bulk orders (CIF/FOB terms). It’s common to request free samples or MOQ quotes before committing to a distributor. In my own experience, building relationships directly with factory representatives helps navigate price fluctuations and ensures consistent on-time delivery, reducing risk of supply disruption on critical projects.

MSDS, REACH, and Safe Handling: Keeping Operations Compliant

Every chemical buyer or end user needs transparent access to material safety data sheets (MSDS), safety data sheets (SDS), and any available technical data sheets (TDS). (S)-1-Boc-2-(Aminomethyl)Pyrrolidine falls under “hazardous chemical raw materials” for customs and EHS teams. The MSDS typically covers properties like melting point, boiling point, specific hazards, accident procedures, and first aid measures. Global companies I’ve worked with rarely accept supply without validated MSDS documents—they form the foundation for internal risk assessment, insurance, and regulatory audits. Suppliers keeping up with REACH registration and updated GHS labeling signal a commitment to long-term partnership.

Purchasing, Demand Reports, and Market Policy Trends

Market demand for (S)-1-Boc-2-(Aminomethyl)Pyrrolidine rises with increased global focus on new drug launches, especially where custom peptide synthesis or chiral intermediates are required. Buying managers track supply policy shifts—whether China introduces new export controls, logistics costs swing, or new REACH-related restrictions get enforced—these impact RFQ (request for quote) practices. Distributors and end users looking to lock in bulk, OEM, or wholesale supply deals monitor market intelligence reports and frequently request updated pricing and stock positions from chosen China-based factories. Across my own time supporting chemical procurement, direct contact with manufacturers and regular pricing updates have always provided a negotiation edge in dynamic markets.

Practical Applications and Industry Use Cases

Pharmaceutical R&D teams use (S)-1-Boc-2-(Aminomethyl)Pyrrolidine mainly as a precursor or chiral intermediate in API synthesis. The protected amine group (Boc) facilitates stepwise build-up of complex molecules, a technique I’ve seen adopted in both cancer drug and antiviral development projects. Materials researchers explore its structure-property relationships, using data from suppliers to tweak molecular design. Applications include solution preparation for pilot-scale batches, so quality and batch consistency matter for reproducible results. In commercial production, demand spikes often track with global clinical trial cycles—a dynamic I’ve personally noticed working with overseas market reporting teams. Rapid access to reliable, quality-controlled material enables innovation and speeds project timelines.

Integration Into Global Supply Chains: Challenges and Solutions

Across continents, integrating (S)-1-Boc-2-(Aminomethyl)Pyrrolidine into supply chains requires more than just a purchase order. Customs and import/export processes rely on accurate HS Codes and up-to-date certification documents (TDS, SDS, ISO, GMP certificates) attached to every batch. Environmental and safety teams check for potential hazardous or harmful chemical classifications and ask for batch certificates showing purity and lot traceability. From my own procurement background, connecting compliance managers directly with suppliers in China has often smoothed out routine frictions in the order-to-delivery cycle. Proactive conversations solve problems before they become shipment delays, and regular audits keep quality at the expected level.

Moving Forward: Smart Chemical Sourcing Strategies

Buyers in the chemical market for (S)-1-Boc-2-(Aminomethyl)Pyrrolidine benefit from clear “buy-inquiry-sample-MOQ-quote” processes, with repeat customers gaining leverage in pricing and flexible payment (LC, TT, etc.). Keeping up with wholesale and distributor networks, and leveraging direct factory channels, can open up access to early-bird pricing or new supply if market shortages emerge. Global market demand moves fast—so companies equipped with solid contacts, full documentation (REACH/SDS/ISO/SGS etc.), and a sharp watch on China supplier trends adapt quicker to any sudden shifts. My own experience proves that the most resilient buyers blend technical acumen with strong supplier relationships, ensuring every batch of raw material helps move their business forward.