Working in the chemical supply chain, I have watched demand for specialized intermediates, like (S)-1-Benzyl-3-N-Boc-Amino-Pyrrolidine, continue to surge as pharmaceutical and biotech markets expand. The CAS number for this molecule opens the door for researchers searching for reliable suppliers, but the world behind it carries much more complexity. The chemical formula C16H22N2O2 gives you a good idea of its molecular heft and reactivity. With a purity of above 98% in reputable factories, the solid usually appears as a white to off-white powder and shows a specific density around 1.1 g/cm³. Researchers and manufacturers want clear confirmation on specifications — HS code (several sources list 2933990090 for pyrrolidine derivatives), molecular structure, boiling point around 383°C, and documentation concerning crystalline form, melting point, and solubility.
Navigating China’s chemical markets gives you a front-row seat to how factories place quality control at the center of their process. With GMP-compliant plants based across Shandong, Jiangsu, and Zhejiang provinces, OEM and private-label options offer buyers flexibility under strict ISO and SGS certification. The direct-from-factory route means greater pricing transparency — Li Er Chem, Sinochem, and a few others regularly list bulk cost between USD 110–180 per 100g (FOB Shanghai), much lower than Europe or North America. Policies tied to REACH and local registration shift each year, nudging international buyers to seek documented MSDS and SDS for customs and logistics. Requests for SGS or TDS (Technical Data Sheet) are frequent, as many importers try to minimize guesswork. Halal and kosher certifications, once rare, now often accompany shipments, especially for multinationals with strict audit requirements.
Anyone who’s spent time at a research bench or in pharmaceutical purchasing knows value comes from reliability and safety. (S)-1-Benzyl-3-N-Boc-Amino-Pyrrolidine acts as a chiral building block in asymmetric synthesis, crucial for creating enantiomerically pure drug compounds. Advanced organic synthesis depends on stable, predictable intermediates to keep timelines realistic. An effective protection group on the amine side, like N-Boc, changes the way intermediates link up in drug candidates, especially where regulatory approval pivots on chirality. Bulk buyers in APIs, agrochemicals, and materials science want documentation to support purity, hazards, and possible reactivity — toxicological data, flammability, environmental fate. For any lab, knowing molecular weight (274.36 g/mol), compatibility in different liter solutions, specific density, solid vs. flakes vs. pearls, and shelf-life matters. Some seek custom packaging – from 10g research vials to 25kg fiber drums for full-batch manufacturing.
SDS and hazard data don’t just fill a compliance checkbox; they ensure safety teams can train accurately. (S)-1-Benzyl-3-N-Boc-Amino-Pyrrolidine has moderate potential as a skin or eye irritant, so proper PPE, storage under inert gas, and cool, dry conditions cut risks. Some buyers also watch for free sample policies or purchase minimums (MOQ), especially if running multiple candidate screens. Distribution practices in China, India, and Western Europe highlight the importance of clear batch tracking and validated supply lines. Certifications regarding quality — ISO9001, SGS, Halal, Kosher — reassure international teams as they scale from sample stage to production. Policies regulating restricted or hazardous chemicals, particularly under EU REACH, impact market dynamics, pricing, and allowable applications.
Sales teams in both China and global hubs streamline the inquiry and quotation process by maintaining flexible sales terms. Minimum order quantities typically start from 1g for research purposes, scaling to 100g, 1kg, and bulk barrel orders for contract manufacturing or long-term distribution. CIF (Cost, Insurance, Freight) and FOB (Free On Board) options shape landed costs, and savvy buyers request quotes for different shipping and payment terms to match their project timeline and budget. Market demand in the last 12 months shows a steady upward trend, backed by growth in R&D for both APIs and chiral intermediates. Every year, deeper market reports and policy updates shift the landscape a little further, emphasizing the need for real-time supply data and reliable cost estimates.
Each purchasing round brings a fresh set of checklist items — certificates of analysis, MSDS, stability reports, technical sheets, and customs paperwork. Laboratories and procurement offices lean on documentation as a core requirement, not an optional extra. This builds trust in the chemical-buy-supplier relationship. In practice, experienced importers verify batch numbers, production dates, and any history of regulatory action to avoid reputational risk. Distributors expedite these details for both free sample programs and bulk wholesale to demonstrate ongoing reliability. OEM and custom synthesis contracts emerge where ready-made stock falls short, and international collaboration continues to tighten quality requirements through standards, audits, and third-party lab verification.
Anyone buying in 2024 watches global policy changes. New REACH and ISO requirements, updated hazard classification, and sustainability trends change sourcing practices. Applications in chemical synthesis, pharmaceutical R&D, and custom manufacturing depend on traceability and regulatory alignment. A growing number of buyers require documentation on supply chain transparency, waste protocols, and environmental controls before placing repeat orders. Inquiries combining application data, structure, and price with up-to-date policy give a clearer picture than generic catalog listings could offer. By focusing on transparent supply negotiations, market demand forecasts, and robust certification trails, (S)-1-Benzyl-3-N-Boc-Amino-Pyrrolidine sets a standard for specialty intermediates worldwide.
