Walk into any modern materials or pharmaceutical lab and you’ll see how the smallest molecules make the largest differences. S-(-)-1-Benzyl-3-Hydroxypyrrolidine, a tongue-twister in name, stands out among specialty raw chemicals. On the books, you’ll spot it under the CAS number 902836-81-1, sometimes tied to the HS Code 2933399090, flagging it for customs and import-export regulation. The structure—benzyl-anchored, with a pyrrolidine ring and a single chiral hydroxyl group—grabs attention for enantiomeric purity, vital for pharmaceutical intermediates.
Labs and purchasing managers want exact numbers, not only names. S-(-)-1-Benzyl-3-Hydroxypyrrolidine features a clear structure: C11H15NO as its molecular formula, showing up as a solid—powder, fine flakes, sometimes crystalline. Specific density consistently pegs near 1.1 g/cm³, and reliable suppliers always include an up-to-date MSDS outlining safe handling, storage, and hazard categories. It isn’t considered a liquid crystal but flows into various organic solvents, opening doors to broad synthesis applications. Knowing the solid form, moisture sensitivity, and storage temp guides buyers on warehouse planning. Listing all physical specs—melting range, appearance, chemical stability—helps technical teams crosscheck if the batch meets process or analytical standards.
Navigating supply from Chinese manufacturers means watching not just price per kilogram, but the wider net: REACH pre-registration, ISO adherence, GMP manufacturing, plus Halal and Kosher certificates. Factory price from a China-based supplier, especially when offered CIF or FOB Shanghai, often undercuts distributors in Europe or North America. A typical inquiry includes required HS Codes, order MOQ, and whether bulk, 20kg drums or 100g samples ship with the right safety paperwork—SDS/TDS always requested by regulatory teams on the buyer side.
Every year, global demand shifts as new pharma projects boom—a single patent extension or regulatory approval can drive sudden bulk requests. S-(-)-1-Benzyl-3-Hydroxypyrrolidine finds regular use building chiral centers in drug molecules or in fine-chemistry applications where ring fidelity and specific enantiomeric purity flip trial results. Analysts keep an eye on market reports published quarterly, noting price swings and changes in customs duties. Tightening policy in Europe, for instance, demands every batch come with SGS/ISO certificates, and distributors carrying OEM/private-labeled versions stress full traceability.
Quality always drives the discussion for chemical buyers—poor purity or uncertain chiral ratios can derail months of R&D work. Responsible manufacturers publish Certificates of Analysis, batch-specific test results, plus REACH, MSDS, and all relevant safety documentation. For a chemist or purchasing supervisor, transparency about potential hazards, stability in cold storage, and shelf-life under normal atmospheric conditions justifies selecting one supplier over another. Talking with end users in the pharma sector, they look at more than just price—they need materials they trust, materials with performance data, bio-compatibility flags, and raw material track record.
Global shipping costs hit everyone. Delays in shipment or inconsistent quality can have ripple effects up and down the pipeline—especially when dealing with complex organic synthesis and OEM formulations. Sourcing S-(-)-1-Benzyl-3-Hydroxypyrrolidine directly from a manufacturer in China means ensuring language barriers do not block clear specs and labs receive high-purity solid, not a poorly handled or aged powder. I’ve seen firsthand what happens when batches get delayed: missed production windows, recalculated project budgets, and very unhappy clients. That’s why developing steady communication with suppliers, insisting on sample shipments for each large batch, and getting everything from factory price quotes to bulk CIF shipment details in writing forms real risk management, not just ideal-world policies.
Talking with formulation scientists and regulatory teams, S-(-)-1-Benzyl-3-Hydroxypyrrolidine stays popular because these kinds of chiral pyrrolidines anchor a wide range of syntheses. You’ll find it as a valuable intermediate for crafting antihypertensives, antivirals, and advanced agrochemicals. Chemical property—stability, chiral recognition, controlled reactivity—really matters at each stage, whether running pilot scale for a new drug or ramping up an existing generic. Regulatory applicants pull from TDS/COA files, crosschecking batch purity, hazardous material classification, and if the product matches a safe/laboratory-grade label. Occupation health teams want clear hazard labeling: is it harmful by inhalation, what PPE is needed, does the MSDS flag it as a hazardous chemical? I’ve seen top firms delay purchasing until a supplier can provide not just GMP and SGS attestations, but actual proof of safe, consistent sourcing.
Ordering S-(-)-1-Benzyl-3-Hydroxypyrrolidine means more than itemizing cost. Buyers price out free samples to test in-house, then request quote for both small- and large-scale supply. Direct communication focuses on available stock, shipping method—FOB or CIF—and expected timeframe from inquiry to final delivery. MOQs spark negotiation, especially for new distributors looking to expand reach in high-growth sectors. In the background, buyers run their own market demand assessments, tracking seasonal spikes and policy updates that impact cost.
Tougher environmental regulations, especially in the EU and North America, push both buyers and manufacturers toward greater compliance and documentation. New ISO and SGS certifications improve transparency. Buyers want their suppliers to back claims with real lab results, up-to-date regulatory filings, and proof the batch matches both Chinese and global standards. Those who adapt quickly, producing clean, chiral, and safe pyrrolidine intermediates, promote themselves directly to research buyers, clinical trial partners, and high-tech materials firms across the globe.
