Pyrrolidine, 2-(3-Fluorophenyl)-, (2S)-, CAS Number 1263283-52-4, brings a level of performance and flexibility that’s hard to overstate in pharmaceutical and specialty chemical manufacturing. Anyone who’s worked in either sector will recognize this compound’s importance, especially as research keeps pushing for reliable, pure intermediates. The unique structure, marked by a 3-fluorophenyl group and a pyrrolidine ring in the (2S)- configuration, serves up serious utility for synthesis—not just in bench-scale experiments, but also in full-scale manufacturing lines where trace impurities and chiral quality can turn into real-world obstacles overnight.
A chemi-buy or procurement team looks at more than a name on a data sheet before making decisions. Suppliers and distributors list Pyrrolidine, 2-(3-Fluorophenyl)-, (2S)- as a solid (sometimes crystalline, sometimes fine powder) with a molecular formula of C10H12FN, offering a specific density that hovers near 1.13–1.21 g/cm³ depending on crystal form and water content. Its HS Code for shipment is 2933399090, and on the ground, it appears as pale flakes or sometimes a white powder—details a quality assurance manager won’t skip over. Flammability, hazardous and harmful categorization, raw material traceability, and MSDS availability stay at the center of safe handling conversations. The reach for comprehensive SDS, TDS, GMP-ISO-REACH certification, and traceable batch numbers isn’t just an office habit but a compliance reality, especially for exporters facing both Americas and European Union customs.
Sourcing out of China has changed the landscape for any global procurement team hunting Pyrrolidine, 2-(3-Fluorophenyl)-, (2S)-. Factories in Shanghai, Jiangsu, and Shandong push out impressive quantities, often with GMP, SGS, ISO, and OEM backing, ready for both distributor and direct buyer requests. Factory price ranges can surprise newcomers—bulk deals, CIF/FOB options, and direct-from-manufacturer quotes let both research labs and pharmaceutical companies secure material without burdensome markups. Global buyers now issue bulk, CIF, and FOB purchase orders or inquire about MOQ and free samples directly through online inquiry forms, and the speed at which they get quotes or MSDS files reflects just how digital and competitive this sector now feels. In markets where raw material shortages have nudged prices up, having access to a responsive, GMP-certified Chinese supplier tends to make a critical difference in cost control.
Most of the action takes place in pharmaceutical synthesis, especially where chirality and fluorine substitution open up routes to more targeted, stable, or bioavailable candidate molecules. R&D labs lean on this intermediate for a wide spectrum of active pharmaceutical ingredients (APIs), many aimed at neurological or pain-management therapies. There’s steady demand from agrochemical researchers too, who probe nitrogen heterocycles for new crop-protection solutions, and even from electronics companies, where niche liquid crystal precursors set new performance standards. As a supplier, offering TDS, REACH data, free research samples, or even halal/kosher certification often means the difference between an inquiry and a closed sale—especially with the organic consumer and global halal market both growing at double-digit rates. Most requests stem from buyers searching for bulk supply, discrete packaging (25kg drums, 1kg foil bags), and complete SDS documentation.
In my experience, warehouse managers and logistics teams rarely overlook safety. Pyrrolidine, 2-(3-Fluorophenyl)-, (2S)- is classified under hazardous goods by shipping firms—this means clear labeling, segregated storage, spill protocols, and, above all, a detailed MSDS. Risk assessments often turn up skin and eye irritation, sometimes even more serious toxicological flags, depending on exposure and purity. Without proper gloves, goggles, and fume hoods, you invite regulatory citation or worse. Chinese manufacturers who supply SDS, batch certification, GMP documentation, and meet SGS or ISO audits put buyers at ease, not just for compliance but for peace of mind when shipping across borders. A recent trend sees more requests for API-grade and food/pharmaceutical-grade product, not just technical grade, echoing rising regulatory scrutiny worldwide. Market-savvy buyers often request insurance, traceability certificates, and sample COA before proceeding with larger MOQ—an extra layer of verification that has become almost expected.
Market data from 2023–2024 signals a moderate climb in both price and demand for Pyrrolidine, 2-(3-Fluorophenyl)-, (2S)-, especially in Asian and European catalogues. Frequent navigation between CIF and FOB contract terms tells me buyers hope to shave shipping charges, but fluctuating costs for raw starting reagents (like fluorobenzene derivatives and pyrrolidine) still ripple downstream. Over the last year, factory price ranges typically land between $135 to $220 per kilogram, though material purchased in small bottles or below MOQ almost always carries a surcharge. Inquiries for bulk, OEM, and custom packaging options have doubled, which hints at growing confidence in the China supply base—buyers are less worried about long lead times, as digital inquiry and quote systems become more responsive and less prone to documentation bottlenecks.
Practical buyers keep a sharp focus on the full lifecycle of procurement: not just a good quote, but verified sample, insurance, and customs documentation, matched against stringent GMP or ISO standards. I’ve seen the difference between a factory that provides REACH, Halal/Kosher, and SGS documentation up front and one that fumbles through after an order—purchasing managers rarely stick with the latter. Quality certifications, full audit histories, and distributor references weigh as much as price per kilo or density specification. Many jump to direct video meetings or site visit requests to confirm manufacturing capabilities and limit risk, especially for high-purity or hazardous shipments. As policy changes in China continue to affect the chemical export market, regular market demand report checks and policy alert monitoring will help buyers keep ahead of shortages and price spikes. For buyers needing continuous supply, establishing direct relationships with established China-based manufacturers—with assistance from export agents, if needed—often brings down both cost and compliance headaches, particularly for markets demanding comprehensive certification and detailed COA, TDS, and SDS records every step of the way.
