N-Boc-3-Pyrrolidineacetic acid, a well-recognized intermediate in pharmaceutical synthesis, lands on the radar for chemists and R&D managers looking to streamline their synthetic routes. This compound, with CAS number 146925-02-6, brings a unique structure to the toolbox: a pyrrolidine ring attached to an acetic acid with a tert-butyloxycarbonyl (Boc) protecting group. Most who deal with organic synthesis or peptide research find its purity and reliable sourcing essential. It acts both as a valuable building block and an intermediate to specialized drug targets. As research expands into new treatments and APIs, the demand for authentic and compliant N-Boc-3-Pyrrolidineacetic acid keeps building up.
For anyone looking to purchase or utilize N-Boc-3-Pyrrolidineacetic acid, checking molecular details and formal documentation proves critical. The molecular formula stands as C11H19NO4, delivering a molecular weight of about 229.28 g/mol. Its classification as a solid, typically found as a white or off-white powder, assists analysts with quick identification. Density numbers and melting points hover in ranges familiar to lab professionals, though specifics may shift slightly by batch and supplier. Structure matters deeply for its reactivity, so confirming lot-to-lot consistency means more than just a box checked on a certificate of analysis; it saves headaches during scale-up. For chemists qualifying new suppliers out of China or comparing global players, seeing the HS-Code 2924199090 streamlines customs clearance and import planning. Proper storage — in cool, dry, and sealed conditions — keeps its Boc group intact and maintains the product in prime condition for long-haul use.
Laboratory managers and buyers grow wary unless N-Boc-3-Pyrrolidineacetic acid comes with up-to-date MSDS (SDS), TDS, ISO, GMP, and possibly REACH records. Many procurement teams track down suppliers who can back up their stock with certifications like SGS audit reports, Halal, Kosher, or OEM quality records, especially when targeting multinational or regulated markets. Checking the latest MSDS sidesteps exposure to hazardous effects — mild irritation to more serious hazards in case of mishandling, especially in unventilated workspaces. Documentation gives peace of mind, and helps meet requirements on-site and across borders. For medical or large-scale drug production, buyers require GMP-factory sources for every lot; for non-pharma, ISO-certified and possibly REACH-registered materials check all the boxes. In every case, buyers ask for and expect more than just paper; they need traceability and responsive after-sales support in English, with transparency into batch records and compliance programs.
End users tackle plenty of questions before any purchase or bulk order. Many chemical distributors spread their reach across China, offering N-Boc-3-Pyrrolidineacetic acid with a range of package sizes — from gram-level R&D vials to multi-kilogram drums for process or scale-up plants. For buyers in North America, EU, or South America, the typical inquiry covers not just lab samples (free or paid), but minimum order quantities (MOQ), lead times, and CIF or FOB-based global shipping options. Factory prices in China typically undercut other supply chains, but shipping times, regulatory paperwork, and payment terms can offset initial savings. Market reports and price trackers suggest steady growth due to pharmaceutical and fine chemical demand. Experienced buyers look for real-time quotes, bulk purchase discounts, clear after-sales response, and transparent customs support. To secure repeat business, reliable suppliers issue technical support, custom synthesis, and OEM or white label solutions, giving multinationals the flexibility to scale or brand as needed.
Pharmaceuticals clearly drive most of the market for N-Boc-3-Pyrrolidineacetic acid, as it conveniently enables peptide synthesis, drug candidate creation, and route scouting for many blockbuster molecules. The ease of the Boc-protected group cuts down on side reactions, simplifying purification, and saving hours on post-reaction workups. Custom organic syntheses, agrochemical discovery, and material science sectors also dip into this pool, leaning on its solid powder form for accurate dosing and safe storage. Chemical engineers engaged in kilo-lab or pilot-scale runs depend on parameter reproducibility and batch documentation for their data integrity. Beyond the bench, QA departments compare finished material against the supplier’s TDS and SDS, flagging inconsistencies before they hit downstream processes or clinical trials.
Much of a buyer’s confidence in N-Boc-3-Pyrrolidineacetic acid comes from hands-on experience with supplier response times, general after-sales support, and no-surprise import processes. Shipment checks for packaging, label integrity, and clear hazardous or non-hazardous categorization build trust. Factories with ISO certification or GMP background gain a reputation for reliability, not only from strong internal controls, but also from smooth document handover in audits or regulatory submissions. Regulatory pressure has increased, as more buyers ask for REACH compliance and prefer green, sustainable raw materials over riskier historic options. Updated SDS sheets support on-site employee safety, helping supervisors address spills, exposures, or waste issues. My own sourcing projects have benefited from close relationship building with technical managers, not just salespeople, as their technical teams often provide deeper application guidance, suggesting solvent compatibility, optimal storage, or batch-specific handling tips that protect both lab teams and final product quality.
Even with hundreds of suppliers globally, raw material bottlenecks sometimes cause sudden pricing spikes or delivery gaps, especially where end-users fail to forecast or when policy changes impact raw chemical imports. Market data points to an expanding need for high-purity intermediates, with buyers negotiating reduced lead times or payment flexibility to secure just-in-time shipments. Local regulations, export controls, or new biohazard labeling from authorities like ECHA or US-EPA change reporting requirements, pushing suppliers to issue more detailed technical and compliance documentation. The future looks bright for suppliers who adapt nimbly to digital quotes, instant sample shipping, and digital traceability from batch synthesis to end-user receipt. Investing in strong relationships, and following up on their SDS, TDS, and REACH notices, protects all parties and helps both new and established buyers move from trial purchase to stable, repeat partnerships. New entrants to this market learn quickly that chemical supply choices tie directly to lab productivity and regulatory speed, making supplier trust every bit as vital as price per kilo.
