Stepping into any pharmaceutical development meeting, people look for purity, reliability, and consistent supply. (R)-1-Benzyl-3-hydroxypyrrolidine sits on many order forms for good reason. As a raw material, it fills an important slot in daily research and drug manufacturing routines. This compound, with a CAS number of 87120-72-7, wears a lot of hats in intermediate synthesis work, especially where the precise stereochemistry of (R)-configuration makes or breaks an active pharmaceutical ingredient. When project managers compare chemical-buy options, factory price tags and the promise of repeatable GMP manufacturing in China mean more than slick sales pitches ever could.
Take a closer look at its skeleton. The backbone of (R)-1-Benzyl-3-Hydroxypyrrolidine includes a pyrrolidine ring, a benzyl group, and a hydroxyl group tucked in at the third position. The precise structure defines its molecular property and application. Chemists see it in forms ranging from solid powder to flakes or pearls, and even as specially prepared solutions measured by the liter. HS Code identification and molecular formula (C11H15NO) pinpoint its track through customs and import controls. Its specific density and handling instructions also land front and center in both the MSDS and TDS sheets handed across labs and shipping docks.
Global supply runs on more than chemistry: policy, export rules, and factory routines weigh just as heavy on the final CIF or FOB quote you see. China's mature manufacturing base can offer a sharp balance of GMP compliance and satisfying regulatory checklists such as REACH, ISO, and SGS. I’ve seen budgets swing sharply based on factory price versus the transit costs to American, European, or Indian buyers. Lab-scale sample requests, distributor bulk contracts, and one-off purchases each draw quick feedback loops between MOQ, lead time, and storage. Buyers push for consistency, and the sharpest suppliers publish third-party-tested SDS safety profiles before serious orders land.
Behind every promising quote, factory and distributor paperwork trails matter: MSDS sheets outline safe and hazardous handling, waste disposal, and exposure guidelines. The compound does bring some harmful or hazardous flags, just like any active intermediate. Warehouse managers know the cargo’s UN number, specific density, and storage recommendations keep insurers and auditors satisfied. On the certification front, demand for ISO, Halal, and Kosher certificates rises each year. Quality-minded buyers have yet another checkbox: OEM manufacturing capability with full traceability from raw material to final drum or flask.
Product demand peaks and valleys often ride the waves of patent filings, new API launches, and regulatory shifts. Buyers from sectors beyond pharma, including specialty chemicals and flavors, have their eye on this molecule. Market news tends to focus on supply chain risks, China’s export policy headlines, or new distributor partnerships. Inquiry, sampling, and quote requests surge when core raw materials become hard to source due to logistics delays or sudden tariffs. Keeping one eye on REACH registrations and the other on shipment policy changes has been part of my routine. Free sample offers and aggressive policy shifts from leading manufacturers regularly shake up how distributors pitch their warehousing options.
Sourcing goes beyond finding the lowest price, though factory price listings drive early negotiations. In-house audit teams check GMP records, seek full TDS/SDS documentation, and require transparent in-house or third-party quality test data. Direct communication with supply chain managers in China bridges time-zone gaps, especially for distributors needing regular, almost just-in-time deliveries. Experience tells me nothing replaces seeing certification proof, such as REACH approval or ISO/SGS batch reports, before a purchase order moves forward. Halal or Kosher-certified product sometimes spells make-or-break for markets in Southeast Asia or the Middle East. Finding a chemical-buy partner means more than a handshake; product traceability through OEM and clear hazard markings back up every long-standing partnership.
Supply stability comes down to forward planning. Companies invest in multiple supplier relationships and keep buffer stock against sudden market surges. Staying in touch with policy changes in China—whether factory shutdowns, holidays, or updated export restrictions—protects downstream project timelines. A sample and MOQ-driven approach cushions purchasing against unforeseen regulations or shifting certifications. For newer market entrants, regular audits and third-party quality certifications aren’t luxury add-ons; they build trust with both buyers and regulators. As the market expands, application notes and safety sheet updates provide working chemists, buyers, and regulatory teams with real tools to interpret and manage all material properties, from specific density to hazardous classifications.
