(S)-3-Pyrrolidinemethanol, a chiral alcohol, appears as a key player in the pharmaceutical and fine chemical sectors. This material, with CAS Number 100212-62-6, presents itself as a white or off-white solid, often powder or crystalline in nature. With a molecular formula of C5H11NO and a molecular weight of 101.15 g/mol, it emerges as an intermediate that chemists and process engineers constantly seek in drug synthesis, agrochemical production, and specialty chemistry. It blends into liter solutions for various lab or industrial procedures. Purity specification, such as 98% or higher, density at 1.06 g/cm³, and melting point ranging from 36 to 39 °C, all form part of the technical data you find on a supplier’s catalog or in a detailed MSDS (Material Safety Data Sheet).
Confident handling of this raw material comes down to knowing its structure: a pyrrolidine ring with a methanol group on the third carbon. Chemists work with the S-configuration for enantioselective applications. HS Code 2933399090 applies in customs. The physical form, whether flakes, solid powder, pearls, or sometimes a liquid crystal, affects storage and downstream processing. The solubility in water and polar solvents gives it that versatile edge in organic synthesis, API development, and even some materials science trials. MSDS covers flammability, labeled as harmful, requiring gloves, goggles, and good ventilation. As with many reagents, safe transport—by air, sea, or truck—relies on proper UN packing, respecting all REACH and RoHS rules. Some buyers focus on OEM and branded supply, looking for certifications like ISO, SGS, Halal, or Kosher, which play a larger role as global pharmaceutical supply chains start prioritizing traceability and compliance.
The supply side, mainly driven by factories and manufacturers across China, stays dynamic. Factories with GMP (Good Manufacturing Practice) certification stand in the middle, balancing bulk price offers with quality expectations. Factory price quotes in China often attract distributors and direct buyers who look for both low cost and stable logistics. CIF and FOB shipments remain standard for bulk orders. MOQ (Minimum Order Quantity) policies vary: buyers can ask for a sample or liter quantities to test reactivity before scaling up. With demand focused on pharmaceutical intermediates and fine chemical reagents, global market reports point to steady upward movement in usage, especially from Europe and North America. Price fluctuates with purity, demand at the moment, shipping route, and service level. Reliable suppliers typically show their REACH registration, offer free samples for larger inquiries, and update buyers on new supply regulations or export policies.
In pharmaceutical manufacturing, (S)-3-Pyrrolidinemethanol plays a decisive role in synthesizing chiral drugs, specifically acting as a precursor for molecules requiring stereoselectivity. Beyond pharma, it finds its way into advanced agrochemical synthesis, special coatings, and even electronic materials as a niche modifier. The specific density and molecular structure influence its reaction pathway. Importers seek detailed TDS (Technical Data Sheet) and SDS (Safety Data Sheet) for plant safety audits, as well as evidence of quality certifications and batch-specific COAs (Certificates of Analysis). Developers who purchase from China-based manufacturers look for GMP, ISO, and OEM contract options, as market feedback regularly shows efficiency and cost savings through direct sourcing as opposed to layered distribution. In my own experience, project managers and R&D teams become fixated on assurance: REACH compliance, trace traceability, and rapid shipment turnarounds match growing project schedules and regulatory audits.
Handling a chiral alcohol like this involves real care: labeling, secondary containment, and staff training center around MSDS-provided information—emergency measures for inhalation or skin contact, proper storage temperatures, and the importance of sealed, tinted containers. Purchasing managers push for the right paperwork—customs-ready HS Code details, full batch documentation, and quality certifications. Companies with strong supply reputations back every liter or kilogram of product with technical support, ensuring safe application in R&D and plant environments. Some buyers ask for Halal, Kosher, or even customized branding for downstream processes, amplifying the product’s reach across food, pharma, and specialty chemical channels. New policy trends—like tougher EU safety requirements or updated China export checks—can slow delivery or raise prices, so buyers watch global news and policy shifts closely.
Getting your hands on (S)-3-Pyrrolidinemethanol means understanding the local and global marketplace. Chinese suppliers typically accept mail, web, and even instant message inquiries. Buyers usually head to direct sales platforms, B2B chemical ecommerce, or reach out by email for up-to-date bulk or FOB/CIF offers. Samples arrive by express courier; confirmation of reliability comes through recent COAs and documentation. Bulk buyers negotiate pricing by purity, actual demand, and contract length, while distributors may chase exclusive deals or geographic rights. Companies stay alert to free sample offers and monitor feedback from peers about supplier consistency and turnaround speed. Market reports help keep track of trends in Europe, the US, and India, showing who’s pushing bigger volumes, what’s raising prices, and how quickly the leading factories fill new orders. Digitized supply chains, QR tracking, REACH, SDS, quality audits, and GMP/ISO-certified outputs all matter for both buyers and sellers, making genuinely sourced (S)-3-Pyrrolidinemethanol an essential tool in any advanced chemical project.
