3-(N-Boc)-Aminopyrrolidine: Industry Demand and Market Insight

What is 3-(N-Boc)-Aminopyrrolidine?

3-(N-Boc)-Aminopyrrolidine carries plenty of significance in the pharmaceutical and fine chemical industries. Its CAS number points to a structured molecule where N-Boc protects the amino group, which unlocks plenty of synthesis options. This compound, C9H18N2O2, generally presents as a white to off-white solid, sometimes found in flakes or granules. Density lands near 1.1 g/cm3. HS Codes for customs and international shipping line up under specialty organic intermediates. The molecular structure means it’s prime as a building block for more complex targets, and the Boc group handles compatibility and deprotection needs during multi-step synthesis. Compared to some less stable amines, this one resists moisture and air, which lets it ship in bulk with less headache around quality loss. Keeping molecular data like melting point around 56-58°C and solubility in typical organics helps technical buyers in pharma R&D or agrochemical factories place the right bulk purchase or lab trials.

Product Properties, Raw Materials, and Applications

The Boc-protected aminopyrrolidine comes from controlled manufacturing, usually involving controlled reactions with di-tert-butyl dicarbonate and aminopyrrolidine. Factories in China, especially those running GMP-compliant lines, have focused on keeping impurity levels at a minimum—often confirmed by in-house and third-party SGS or ISO certifications. This compound’s purity comes in above 98% (HPLC), with typical analysis covering NMR and MS spectra. It usually ships as a free-flowing powder or in sealed foil bags, or, for bulk buyers, double PE drums. Some buyers want a liquid solution form, made fresh on demand for just-in-time synthesis or distribution purposes. Listing on a supplier’s SDS or MSDS gives analytical chemists the hazard info—mild eye and skin irritation, so work with gloves and goggles, but no wild hazards like some other materials. Technical data sheets pack further details for factories looking to validate sources or work through REACH or TDS documentation for global dispatch or import demands. Oil and gas, coatings, and advanced materials fields sometimes see growing demand depending on the need for amide bond or N-heterocycle synthons.

Market Trends, Price, and Supply Chain

Interest in 3-(N-Boc)-Aminopyrrolidine tracks rising market demand in China, Europe, India, and the United States. Factory prices in China often come in more attractive for bulk and distributor-level buyers. Most suppliers offer both CIF and FOB quotes depending on whether a client needs door-to-port or delivery-at-factory contracts. Small R&D labs request free samples or low MOQ; full-scale manufacturing players look at multiple tons every season. Recent demand spikes tie to increased generics synthesis and wider use in peptide-based therapies, especially as synthetic routes for specialty actives get more complex. Market reports discuss the policy picture around hazardous materials import and export licenses—smaller distributors sometimes catch delays here, favoring established bulk suppliers with OEM capability and experience navigating customs in the EU and other regulated areas. Prices shift with global supply chain pressure; some seasons favor buyers, others see cost inflation from tight raw material stocks, and specialty reagents producers hold delivery times steady by using local warehousing and working with major shipping partners.

Supplier, Manufacturer, and Certification Considerations

Experienced buyers gravitate to suppliers that show up with clarity on certifications—ISO for management systems, GMP for pharma or food-grade manufacturing, additional halal and kosher certification for sensitive markets. Some buyers require up-to-date REACH documentation for European sales, plus a full pack of SDS and TDS. Many Chinese factories now offer OEM/ODM service, allowing branding or tailored grade supply direct from their line. Bulk inquiries often see the chance to discuss wholesale or long-term contract rates, or even joint development of derivatives or tailored packaging (such as low-dust flakes or moisture-resistant powder packs). Factories answer with rapid technical support, often English-speaking, and dispatch samples within a matter of days for trial purposes. On-site audits have become more common as clients look to lock in multi-year agreements or audit production chains for compliance with both domestic and international rules on hazardous and safe chemical raw materials. Clients looking for a one-stop solution—whether for liter-amount solution supply, kilo-level solids, or custom packed pearls—find value linking up with a single partner for end-to-end project support, markdown on annual volume, and direct shipment with clear customs form completion.

Practical Use, Safety, and Long-term Trends

3-(N-Boc)-Aminopyrrolidine’s structure, Boc-protection, and reliable physical properties bring value to anyone running amidation protocols or looking for pure intermediate supply in bulk. Pharma plants rely on steady MOQ shipments for year-round production, and chemical material factories use the compound’s unique molecular property for heterocycle synthesis. Safety discussions focus on routine PPE—no need for high-level containment, but avoid breathing powder or spilling solution on skin. For every purchase, buyers want up-to-date MSDS and TDS, especially for international transport or scale-up in pilot plants. Recent years bring focus on sustainability and supply chain transparency, so many factories now list their SGS, ISO, and environmental certifications as a routine part of the quoting process. Clients running REACH registration or seeking new distributor partnerships care about these, linking regulatory compliance with long-run product access and pricing stability compared to lightly certified sources. Distributors value full support for OEM, white label, and custom synthesis options to capture new pharma and advanced material customer segments, while factory-direct sellers balance bulk pricing against the need for technical documentation and rapid response on technical and safety questions. Real market growth comes not just from new product launches, but from clear, simple communication and documented support for every lot of 3-(N-Boc)-Aminopyrrolidine shipped.