(2S)-2-Phenylpyrrolidine shows up in the chemical supply chain as a valuable chiral building block. This heterocycle, C10H13N, brings a core pyrrolidine ring that’s fused with a phenyl group in the S-configuration, making it especially relevant for pharmaceutical synthesis. The compound stands out in white to off-white flake, solid, and powder forms, supporting flexibility in different applications. Its molecular structure attracts interest for asymmetric catalysis, intermediates development, and agrochemical manufacturing. Molecular weight lands at 147.22 g/mol, density keeps steady at about 1.06 g/cm³, with melting points ranging from 36 to 41°C. HS Code referencing in customs documentation: generally 2933399090, streamlining tariffs and logistics. Chemists and purchasing managers often pull up the MSDS to double-check for flammability, storage conditions, or handling precautions—in particular, reviewing hazardous material status or potential classification as a harmful chemical.
China rows ahead as the major source for (2S)-2-Phenylpyrrolidine bulk orders. Factories across Jiangsu, Zhejiang, and Shandong provinces, all the way east along that seaboard manufacturing corridor, keep up with demand from both fine chemical and pharma end-users. What’s striking in the Chinese chemical industry is its rapid ramp-up to GMP production lines and ISO/SGS-certified quality controls, which big-name international distributors constantly audit. Factories run both OEM and ODM supply models, supporting custom ratios or bulk-packed orders. Most sellers provide both small quantity samples (typically 1g-100g) and bulk options scaling up to drum or pallet lots. The supply network positions strongly for CIF, FOB, and delivery-at-port terms, keeping costs attractive even in regions seeing increased regulatory screening or tariffs. Factories will send technical data sheets (TDS), full reach safety data sheets (SDS), COA (certificate of analysis), and can supply halal, kosher, and even sample batches shipping with comprehensive packaging and labeling solutions.
Tracking factory price quotes in the specialty amine category holds real value for procurement specialists. Current bulk price benchmarks out of China fluctuate depending on order quantity, purity (routinely ≥99%), and whether GMP or pharma-certified batches are requested. For reference, unit pricing typically drops sharply at the hundred-kilo scale, with additional discounts available for annual contracts and exclusive distribution. Both CIF and FOB terms offer flexibility, with CIF often suiting Southeast Asia, Europe, and North American importers who prefer landed costs. Established distributors may extend free samples, and MOQ (minimum order quantity) regularly sits as low as 100 grams for new accounts or research institutions, but moves up fast for monthly supply agreements.
Pharmaceutical R&D teams hunt for (2S)-2-Phenylpyrrolidine as an intermediate for active drug ingredient synthesis, especially for chiral auxiliaries and ligands. Specialty sectors—like crop protection chemical firms or fine fragrance labs—lean on the material for its stereochemical purity. Chemical properties such as solubility in common solvents, low specific density, and stable crystalline appearance open up formulation options, so it finds use not just in solid raw blends but also as a solution/stock compound in liter-scale labs. Technical specifications help buyers match requirements like color, moisture content, and particle size to downstream industrial processes.
Anyone in chemical procurement needs to watch shifting global policies—think EU REACH, US TSCA, and China's expansion of its own hazardous chemicals catalog. An MSDS is not just a formality. Regulatory documentation, especially for products moving through customs or destined for pharma applications, strengthens compliance while preventing costly import delays. Traceability matters just as much as certification: labs running QA will always demand full batch COA, along with GMP trace numbers and third-party lab results for impurities and heavy metals. Recognition from ISO 9001:2015, SGS, halal, and kosher bodies, not to mention on-site audits, delivers market confidence and maintains access for multinationals sourcing from China, Europe, or India.
Experience shows the best results flow from close work between factory and end user. Sample batches should come early, and a responsible supplier offers immediate answers on both price and technical data. Building a supply relationship means getting direct lines to chemists for technical advice, not just sales staff. Market demand for specialty chiral reagents continues to grow, especially as more pharma companies push into new chemical entity synthesis, which in turn fuels requests for custom batch sizes, tailored purity, and blended delivery options. Partner factories that blend strong technical knowledge, clear export documentation, and a willingness to adapt packaging or shipping terms to customer needs stand out. As regulatory scrutiny rises across regions, buyers put a premium on transparent sourcing, audit-friendly paperwork, and suppliers who keep up with global certifications, making (2S)-2-Phenylpyrrolidine’s market both competitive and innovation-driven.
