Anyone working with chemicals in synthesis or formulation quickly learns the practical value of pyrrolidine derivatives. (2S)-2-Methylpyrrolidine stands apart from other similar compounds due to its molecular structure: C5H11N, with a specific density close to 0.85 g/cm3. With its strong basicity and nucleophilic profile, this compound appears in large-scale pharma and specialty chemical manufacturing. Some solid variants resemble flakes or powderings, echoing what comes out of well-calibrated GMP plant lines. Liquid and crystalline grades circulate, depending on grade and intended use. For many, the hard data provided by an MSDS becomes the first point of reference before any purchase, cementing the importance of transparency in chemical-supply literature.
Take a closer look at its structure and some specific specs: (2S)-2-Methylpyrrolidine, a chiral secondary amine, packs a five-membered saturated nitrogen ring with a methyl twist at the two-position. Pure material typically falls under HS Code 2933999099 (customs, import-export). Its melting point lines up in the standard range for pyrrolidine analogs, so expect ease of handling in room-temperature conditions—no need for complicated storage solutions unless you’re pushing industrial scale. Chemically, this compound appears in pellet, solid, or liquidcrystal forms, each offering different advantages for downstream blending or direct use in organic synthesis as a chiral auxiliary.
If you scout chemical-buy portals or reach out to top-tier China suppliers, you'll run into a competitive factory-price model. Many serious manufacturers operate with GMP-compliant workshops, with ISO and SGS quality certifications you can actually verify. Some even respond quickly to OEM requests or run halal and kosher lines, providing materials that meet a wider range of specifications. Buyers should look past just the headline price. Top suppliers will have raw material traceability and can share their Reach and TDS documentation upon request. Often, you can negotiate for free samples or request a detailed market-demand report if volumes climb into the bulk territory.
For businesses needing (2S)-2-Methylpyrrolidine in quantity, China-based suppliers usually offer the best balance of quality and price, especially under FOB or CIF shipping terms. Minimum order quantity (MOQ) may start at a few kilograms, though some distributors cater to R&D needs with smaller free samples for initial testing. Bulk buyers generally receive tiered quotes, and mature buyers know to check not only price per kilo but also shipment lead time—raw material fluctuations often hit the Asian markets first. Serious distributors, the ones who show flexibility with CIF or FOB terms, tend to keep TDS, COA, and even ISO and SGS certifications up-to-date, making repeat business much less risky.
I’ve seen (2S)-2-Methylpyrrolidine act as both a raw material and a building block in pharmaceutical intermediates, especially where a specific chiral environment dictates selectivity. Its utility isn’t limited to pharma, though: it crops up in crop science and custom synthesis too. OEM demand walks hand-in-hand with advances in asymmetric catalysis, where supply chain disruptions can ripple out and jack up spot prices. That’s the reality for chemical buyers—in strong market years, demand outpaces supply, making factory price negotiation a real skill. Market reports paint the picture clearly—growing application in high-value synthetic routes keeps this molecule in steady demand.
Safety always tops the list for any chemical, and (2S)-2-Methylpyrrolidine comes with a clearly documented MSDS outlining all hazardous and harmful characteristics. As a secondary amine, it will cause irritation, especially at high concentrations, so gloves and eye protection are mandatory during handling. Proper storage under dry, cool, and well-ventilated conditions keeps the risk in check. For logistics teams and warehouse managers, the labeling requirements and documentation line up with global REACH standards, and any reputable supplier will share comprehensive SDS docs up front. For those with large on-site inventory, a rigorous policy for handling hazardous raw materials must go beyond compliance and become part of company culture.
Quality certifications mean more than framed certificates on an office wall. Any sustained supplier relationship in (2S)-2-Methylpyrrolidine hinges on real third-party data (ISO, SGS, Halal, Kosher). As a buyer, nothing builds confidence like an accessible, detailed COA, traceable batch numbers, and transparent testing data. Some buyers prefer companies who publish their TDS and REACH compliance openly on their website. If you’re running a plant on tight tolerances, consistency needs to be more than a talking point—it needs proof. Fixed standards, frequent audits, and external validation offer the best strategy for keeping raw input quality where formulators and end-users actually need it.
Walking the tradeshow floors or tuning into quarterly chemical market reports, it’s clear demand for (2S)-2-Methylpyrrolidine continues to rise, shaped by innovations in pharmaceuticals and specialty materials. China-based manufacturers remain at the core of the global supply network, but recent years have seen a stronger focus on supply chain resilience backed by vertical integration. Buyers now watch for sudden regulatory changes that can hit HS-codes or export quotas, so up-to-date policy tracking forms part of the new buying routine. Modern market intelligence combines real-time pricing with certification and sustainability trends—suppliers that adapt quickly stand out from the crowd. For buyers, sample inquiries and frequent market-checks go a long way in building long-term value.
