2(R)-2-(Trifluoromethyl)Pyrrolidine shows up in specialty synthesis and pharmaceutical intermediates thanks to its specific structure. It has a unique trifluoromethyl group connected to the pyrrolidine ring, giving it boosted metabolic stability and a favorable pharmacokinetic profile. These features turn it into a go-to building block for advanced chemistry and drug discovery work. CAS Number and HS Code matter for anyone trading globally, ensuring smooth customs clearance. As for its molecular property, this compound carries the formula C5H8F3N, and its specific density typically falls around 1.24 g/cm³. Chemists call on its flakes or solid powder forms since these suit both small-scale R&D and bulk manufacturing. Structure-wise, the chirality at the 2-position adds to its value in crafting enantiomer-specific drugs. Material safety data sheets (MSDS) help manage the risks with this raw material, containing info on its hazardous nature and storage requirements.
China stands as the chief supplier and manufacturer for 2(R)-2-(Trifluoromethyl)Pyrrolidine, with most factory prices reflecting intense competition, OEM contracts, and GMP compliance documentation, such as REACH, SGS, ISO, or even halal and kosher certificates. From personal experience handling chemical procurement, picking a supplier in China often brings options for bulk sale, CIF or FOB arrangements, and even free samples for initial quality checks. Factories supporting GMP allow for smooth entry into global pharmaceutical supply chains, especially if I’m looking to sign under NDA or require labeling matched to specific client specs. The market price swings with demand trends in North America, Europe, and Southeast Asia. Large-scale buyers usually negotiate better quotes or get preferred distributor status. MOQ—Minimum Order Quantity—tends to sit at 1 kilogram for bulk operations, but sample requests help smaller shops try out this chemical in a liter solution or crystalline solid.
Handling 2(R)-2-(Trifluoromethyl)Pyrrolidine calls for grounded expertise and understanding of its hazards. Its MSDS, or material safety data sheet, warns about its potential harmful or hazardous nature. In actual lab use, eye protection, gloves, and chemical-resistant clothing help keep the process safe. The compound’s molecular weight and property—especially that distinct trifluoromethyl group—influence volatility and handling procedures. Personally, I watch storage conditions: tightly sealed containers and controlled temperatures (often under 25°C) help guard against degradation. Its physical forms as flakes, powder, or even pearls present dust hazards, so industrial suppliers with GMP/ISO facilities emphasize advanced containment and venting systems. Documentation such as REACH, SDS, and TDS, as well as third-party certs like SGS or OEM labeling, represent quality assurance steps that the best suppliers make easily accessible.
Real-world demand for 2(R)-2-(Trifluoromethyl)Pyrrolidine tracks pretty closely with trends in pharmaceutical R&D, fine chemical synthesis, and expanding API production. Over recent years, global news shows persistent market growth driven by oncology and CNS drug development. Many purchase inquiries land in Chinese suppliers’ inboxes, with bulk CIF and FOB price requests arriving from American and European distributors aiming for steady market supply. For buyers, orders require careful vetting—looking at TDS, COA, and on-request GMP facility audits. My contacts in chemical distribution suggest the process goes smoother with sample runs and formal technical due diligence performed upfront, which hints at how the market’s matured since the days of informal gray-market trading. Most buying cycles see a quote supplied, an inquiry sent out, a sample or MOQ approved, and purchase terms negotiated for bulk, wholesale, or distributor resale. Certification—whether ISO, GMP, halal, or kosher—often forms a prerequisite for access to regulated industries and large-volume demand.
Application areas for 2(R)-2-(Trifluoromethyl)Pyrrolidine appear in new molecule research, chiral drug synthesis, and agricultural chemical development. For anyone making claims in regulated markets, supporting quality with ISO, SGS, and certification seals turns into a baseline requirement, not just a marketing flourish. Halal and kosher approvals open this raw material up for use in multinational production chains, including pharmaceuticals serving specialty markets. Compliance with REACH and other policy directives reflects a broader shift where supply partners in China must document production traceability, residual solvent controls, and EHS policy in technical data sheets. Over time, demand for these chemistries rises, and transparency in hazard classification and storage rules builds trust with regulators and downstream buyers. From my vantage point in the chemical sector, direct lines of communication with manufacturers—sometimes evening calls across time zones—help iron out misunderstandings and prove critical in certificate-heavy deals or special OEM requests.
Moving forward, the clearest solution for safe, affordable, and compliant 2(R)-2-(Trifluoromethyl)Pyrrolidine procurement involves ongoing partnerships with China-based manufacturers offering GMP and REACH-backed transparency. Experienced chemical buyers chase free samples, detailed quotes, and MSDS downloads before pulling the trigger on large purchases. Bulk, CIF, or FOB delivery options let supply chains stay nimble. For the safest material handling, documented training for hazardous chemicals, up-to-date msds review, and properly certified storage sites mark out best practices. For those distributing or importing, double-checking certifications like ISO, SGS, and halal/kosher keeps doors open with end-users needing market-specific assurances. Tracking trends, price reports, and new market policies helps companies capitalize on shifts in demand or regulatory focus, and I lean into these signals whenever sourcing strategic intermediates for advanced laboratory projects or end-product scale-up.
