1-Iodo-5-Pyrrolidinedione: Opening the Gates to Efficient Iodination in Chemistry

Understanding 1-Iodo-5-Pyrrolidinedione as a Chemical Raw Material

1-Iodo-5-Pyrrolidinedione has carved out a unique niche for itself across research and industry labs thanks to its specialty as an electrophilic iodine source. In day-to-day use, this chemical, with CAS number 887-67-2, pops up in synthetic reactions, especially those focusing on iodination of organic molecules. Its structure features the pyrrolidinedione ring attached to an iodine atom, which gives it not only distinctive reactivity but also a set of handling concerns you can’t ignore. Density sits at about 2.36 g/cm³ in its solid state, and depending on the batch, the raw material arrives as pale yellow flakes or a crystalline powder, easy to weigh, measure, and dissolve. Labs sourcing material from China supplier-manufacturer networks usually ask for comprehensive certificates—GMP, ISO, SGS, and even Halal or Kosher certification, depending on the supply chain and end-market. Orders can be scaled from research-size sample bottles right up to bulk CIF or FOB shipments, tailored to custom OEM requirements. Before buying, users nearly always check the MSDS for hazard and handling. The material holds a hazardous chemical classification, so every kilo finds itself under strict regulatory and storage conditions, especially in plants where chemical supply policies reflect REACH or GHS labeling guidelines. The product sports the HS Code 2933990099, and supply updates, market trends, or purchase quotations tally with a global shift toward transparent, certified manufacturing lines to ensure safe use as a raw material across pharmaceutical and specialty chemical factories.

Facts from the Practical Workbench: Properties, Market, Application

Working with 1-Iodo-5-Pyrrolidinedione, professionals often talk about its utility as a safe, solid source for introducing iodine into target molecules, compared to the risks associated with pure halogens. Its molecular formula, C4H4INO2, and melting point, around 210°C, grant it a shelf-stable nature, important for warehouse managers negotiating storage with Chinese supply factories. The solid form means less risk in transit than liquid or gas, so distributors handling bulk CIF or FOB deals appreciate its robust packaging—usually double-layered PE or aluminum foil bags. Labs use it to iodinate aromatics for final drug intermediates, add it into solution for scales from milligram to liter, or drop it into an NMR tube for quick-check reactions. Supplier experience shows market demand building, particularly as synthetic chemists move away from elemental iodine because of its hazardous and volatile profile. Recent application reports highlight this shift, analyzing prices in China, purchase minimums (MOQ), and inquiry-driven processes before buyers commit to a trial sample or full shipment. Apart from synthesis, regulatory officers always dig into Safety Data Sheets (SDS), technical documents (TDS), and reach out to up-to-date literature for safe handling and proper storage specs in light of increasing global scrutiny on chemical supply.

Supply Chains, Quality, and Certification: The Real Story

A consistent feedback from regular customers points toward the value gained by working direct with Chinese factory-manufacturers who handle end-to-end quality audits and certification processes—OEM orders, batch-to-batch SGS or ISO testing, and halal or kosher demands for finished product buyers in Europe and Southeast Asia. Many buyers prefer to negotiate price on a CIF or FOB basis, reducing uncertainty in their supply budgets, while pushing the factory for the most current market price tracking. GMP certification forms the baseline for pharmaceutical clients sourcing this chemical, keeping suppliers on their toes about purity, traceability, and process validation. Frequently, global distributors request REACH, ISO, and even Kosher or Halal certification to open new markets, motivating factories to streamline certification and documentation on every kilo shipped. Bulk buyers typically push for free samples, full COA and MSDS documents, and even customized labeling. Reports show that as more manufacturers in China invest in compliance, international demand grows steadily, benefiting buyers looking to reduce cost without sacrificing quality. If you weigh up the options, the balance consistently tips toward direct partnership with factories that meet all regulatory requirements—including on-site audits, transparent documentation, and clear communication from inquiry to logistics.

Market Demand, Policy Shifts, and Practical Solutions

Growth in market demand for 1-Iodo-5-Pyrrolidinedione links directly to two factors: its ease of use in organic synthesis and tightening regulations on hazardous chemical supply chains. Pharmaceutical companies lean harder on GMP-compliant manufacturers in China, where quality and competitive pricing open doors for scale-up applications. Market reports suggest distributors hunting for updates on factory price or available inventory benefit from clear supply policy, channel access, and up-to-date certification. Importers need specific documentation—REACH compliance, updated SDS in multiple languages, and full TDS packs—to pass customs smoothly. Freight logistics, whether CIF, FOB, or Express, rely on accurate HS Code listing (2933990099), which reflects both the product’s molecular structure and its legal framework under USD or EUR trade regimes. For those looking to buy, available free samples, rapid quote response, and batch certifications tip the scales in favor of suppliers able to guarantee steady material flow. Quality assurance (including full spectrum analytical methods like NMR, HPLC, GC) and scalable MOQ play the biggest role in operational purchasing. Professional buyers search for robust OEM solutions and market-tested certificates, knowing that missing even one link in the supplier chain can disrupt long-standing production schedules and hit compliance budgets hard.

Application Know-How: Using 1-Iodo-5-Pyrrolidinedione Safely and Effectively

Anyone trying to integrate 1-Iodo-5-Pyrrolidinedione into a new workflow pays close attention to MSDS safety recommendations. Trained chemists suit up with full PPE, process the solid with minimal dust, and maintain strict control over storage humidity, especially in larger warehouses. The solid’s relatively high density means easy weighing and batch preparation, which makes scale-up predictable—a key point for pharmaceutical factories doubling their yearly purchase volume. If a buyer leans on supplier support, technical teams from the factory walk them through change controls, REACH compliance, and SGS or ISO batch testing. New distributors often require data verification, cross-checking TDS from manufacturer websites with in-house testing or third-party certification before any bulk purchase. End-user reports from pharma and chemical plants rely on timely shipment—pivotal where late delivery could freeze high-value synthesis lines. Many managers negotiate free samples or small-lot shipments for pilot projects, looking for consistent homogeneity and reliable analytical data (NMR, melting point, loss on drying). For those scaling up, safety checks, lab simulations, and market reports on price trends from China round out a complete procurement strategy.

Improving the Chemical Buying Experience—What Buyers Ask

Working with a host of chemical suppliers, one constant remains: buyers focus on full-cycle service beyond factory price. A smooth transaction means rapid quote on inquiry, MOQ flexibility for market testers, competent technical advice, and up-to-date compliance documentation. Distributors, whether rooted in Europe, the Americas, or Southeast Asia, turn first to suppliers with proven GMP, ISO 9001, SGS, REACH, and OEM ability. Many factories, especially in China, commit to policy changes that reflect global best practices—putting in place transparent logistics, TDS updates, and responsive sales support. Large buyers ask about the HS code, request fresh COA and batch data, check the density and structure directly, and expect clear answers regarding application use, whether in pharma, specialty, or general chemical production. Market-wise, a current report covering application, policy, and shipment pricing gives buyers leverage before locking in contracts. Quality certification—halal, kosher, or other niche-compliant badges—often opens new revenue for distributors, especially if they support technical troubleshooting, bulk shipping, and safe handling for hazardous raw materials. Plenty of purchase managers make use of product-specific inquiry forms, sample request functions, and quote-on-demand services to move fast within cycle times, keeping market demand and production lines perfectly in tune.